UpTone Audio

ISO REGEN

Introduced 2017$325 MSRP

UpTone Audio is a small US direct-to-consumer engineering shop that, by its own description, focuses its resources on design and production rather than marketing, selling primarily online with a limited dealer footprint (UpTone Audio). The ISO REGEN is a galvanically-isolated USB signal regenerator/reclocker built around a Silanna USB isolator chip and a Crystek femtosecond-jitter oscillator; it succeeded the original USB REGEN (of which nearly 4,000 had sold worldwide) and has been reviewed by Stereophile, AudioScienceReview, and AudioBacon (UpTone Audio; Stereophile; AudioScienceReview).

MSRP

$325

Used market · Good

$225

-31% vs MSRP

as of Sep 1, 2026

Sell or trade this Add to my system

MSRP to used market

From $325 at launch to $225 today.

Specifications

Function: Active USB signal regenerator/reclocker inserted between USB source and DAC
Guarantee: 30-day money-back satisfaction guarantee
Parts count: 85 parts
USB hub chip: USB 3.1 hub chip, selected for measured signal integrity
USB vbus output: Up to 1A clean power for bus-powered DACs/headphone amps
Clock oscillator: Crystek CCHD-575 ultra-low-phase-noise "femtosecond" clock
Downstream power: Requires external 6–8V DC supply; included AC-to-DC adapter is world-voltage compatible
Connector options: Standard USB-B or MicroUSB-B adapter (for Chord and similar DACs)
Galvanic isolation: Silanna Semiconductor ICE08USB high-speed USB isolator
Voltage regulation: Five Linear Technology LT3042 ultra-low-noise 200mA regulators; TI TPS7A4700 for clean 5V VBUS output
Compatible upgrade psu: UpTone UltraCap LPS-1.2, bundled at a $50 discount